A few symptoms of B12 deficiency include: Conditions of the small intestine (Crohns disease), anaemia, fatigue, constipation, poor balance, memory loss, shortness of breath, and more
3.4 Changes in serum homocysteine by supplementation route and dosage Analysis of 10 comparisons showed that vitamin B12 supplementation was associated with a mean reduction of 35.8% in serum homocysteine concentrations (Supplementary Table S5)
However, one study on the treatment of children with methylmalonic acidemia and homocystinuria found oral hydroxocobalamine at 1 mg daily to be ineffective in reducing levels of homocysteine
Filling can be effective
The evidence for ghk-cu topical should be weighed by study type, human relevance, route, product quality, and the limits of what has actually been demonstrated